One SNP, rs2179922 located in intron 4 of ESR1 showed and association signal (p = 0.0056) in the male samples from the PIVUS cohort. Homozygote carriers of the G-allele of the SNP rs2179922 were on average 0.90 cm taller than individuals with the two other genotypes at this SNP in the ULSAM cohort and 2.3 cm taller in the PIVUS cohort.

Persistent Organic Pollutants and Inflammatory Markers in a Cross-Sectional Study of Elderly Swedish People: The PIVUS Cohort. Jitender Kumar,

(13) and R€onn et al. (15), where the PIVUS cohort was examined using waist circumference and fat mass determined by dual-energy X-ray absorptiometry, respectively. Since viscerally located fat seems to be the most harmful type in cohort studies, and to investigate whether such metabolites share a common genetic background with type 2 diabetes. A secondary aim was to explore whether the addition of metabo-lites to the Framingham diabetes risk score [9] would improve prediction of type 2 diabetes. Methods Study population We used data that had been generated previously the Vasculature in Uppsala Seniors (PIVUS) cohort study. All individuals who were 70 years of age and liv-ing in Uppsala, Sweden, were invited.

Pivus cohort

The MISS cohort started in 1990 when 40 000 women between 26 and 65 in Skåne were randomly selected to participate in an interview about the risk factors for malignant melanoma and breast cancer. 29 508 (approximately 74%) of women surveyed chose to participate. None of the women had a history of cancer. Background and Purpose: Signs of small vessel disease (SVD) are commonly seen on magnetic resonance imaging (MRI) of the brain in cognitively healthy elderly individuals, and the clinical relevance of these are often unclear. We have previously described three different MRI manifestations of SVD as well as cerebral perfusion in a longitudinal study of non-demented 75-year-old subjects.

risk of hospitalization due to heart failure: a Swedish population-based cohort study. i ett exempel, i s.k.

ID: 177: Name: PIVUS (Prospective Investigation of the Vasculature in Uppsala Seniors) Acronym: PIVUS: Description: The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala.

2018-10-01 Discovery Cohort The PIVUS cohort was used as the discovery cohort. All 70-year-old men and women living in Uppsala, Sweden, between 2001 and 2004 were invited to the PIVUS study (PIVUS-70).15 In total, 1016 people (507 women and 499 men) took part in the investigation (participation rate=50.1%). A second examination 2020-08-04 METHODS: The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort provided plasma samples three times from 2001 to 2014.

2020-10-05

Persistent Organic Pollutants and Inflammatory Markers in a Cross-Sectional Study of Elderly Swedish People: The PIVUS Cohort He is the PI of the ongoing longitudinal cohort study Good Ageing in SKåne with the ULSAM, PIVUS (www.medsci.uu.se/pivus/pivus.htm) and POEM cohorts. Four additional prospective cohort studies (MDC, PIVUS, ULSAM, MRC Ely; Nmax = 8263 In pooled analyses of all cohorts, 139 SNPs at six and five loci were av T Hansen · 2007 — Studies with outcome data of the PIVUS cohort are needed for further validation of the WBMRA method and to determine whether TAS can be used as an No association was observed for the females in the PIVUS cohort. Genetic Traits in Population Cohorts using High-throughput Genotyping Technology The PIVUS Cohort2014Ingår i: Journal of Environmental Health Perspectives, Investigation of the Vasculature in Uppsala Seniors (PIVUS) study2012Ingår i: Human exposome study · PIVUS: kan organiska miljögifter ge hjärtkärlsjukdomar? Sen debut av inflammatorisk tarmsjukdom · SHAPE - Sustainable reduction of metabolomic and proteomic data from six longitudinal, population-based cohort studies (STHLM2, Karma, TWINGENE, PIVUS, ULSAM and GOSH) including Mortality Among Hardmetal Production Workers: Pooled Analysis of Cohort Data in a Cross-Sectional Study of Elderly Swedish People: The PIVUS Cohort. of environmental toxins in the cohort PIVUS; epigenetics, endocrine changes Responsible for data analyses for four Stockholm cohorts within the ESCAPE Seniors (PIVUS) study we have made a much more thorough characterisation of cardiovascular This cohort is now reinvestigated in a similar way at age 75. Results from the PIVUS cohort.

The fact that the longitudinal changes in sTNFR1 were significantly associated with longitudinal changes in GFR over a 5-year period adds additional support for the theory of a causal association. Further studies are needed to shed light on this issue. Small Vessel Disease on Neuroimaging in a 75-Year-Old Cohort (PIVUS): Comparison With Cognitive and Executive Tests Ruta Nylander 1*, Lena Kilander 2, Håkan Ahlström 1, Lars Lind 3 and Elna-Marie Larsson 1 1 Department of Surgical Sciences, Radiology, Uppsala University, Uppsala, Sweden Therefore, we conducted this study utilizing measurements of various circulating POPs in a large population-based sample of men and women aged 70 years from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort (http://www.medsci.uu.se/pivus/).
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70-åriga kvinnor och (f=63%, m=37%) including 233 in the young cohort (20-35y) and 769 in the old cohort (60-83y). 19 Problems Projects underpowered by using only one cohort at a time, LU MPP LU NKCx KI NMC KI NSHDS-VIP UMU PIVUS UU PREV GU RHINE UU 46 Metabolomik i populationer från Uppsala TwinGene - Serum Case-cohort 49 Median concentrations (ng/ml) of PFAS in PIVUS (70 years) vs NHANES (all) We collaborate with professor Lars Lind, Acute and Internal Medicine, related to the PIVUS, ULSAM, EpiHealth cohort studies. We are collaborating with Prof.

Plasma was prepared by centrifugation at 2000 × g for 20 min, then frozen and stored at −70 °C. These individuals were recruited from the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort. ID: 177: Name: PIVUS (Prospective Investigation of the Vasculature in Uppsala Seniors) Acronym: PIVUS: Description: The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala. To our knowledge, PIVUS is the largest cohort with repeated sTNFR1 measurements to date.
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The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala. As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and

Diet is one of our main exposure routes to environmental contaminants.

METHODS: The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) cohort provided plasma samples three times from 2001 to 2014. Individuals maintaining the same zip code throughout the study (n = 399) were divided into a reference (no known PFAS exposure), low, intermediate and high exposure area depending on the proportion of contaminated drinking water received.

Recent analyses using two independent cohorts (ULSAM and PIVUS) showed an association between LOY in blood. 31 Jul 2015 Research Design and Methods: Two community-based cohorts of To our knowledge, PIVUS is the largest cohort with repeated sTNFR1 7 Oct 2014 from two large cohorts, the population-based PIVUS cohort (N = 406, Alzheimer disease Neuroimaging Initiative (ADNI) cohort (N = 724).

Design, setting, and participants: Prospective study using 2 community-based cohorts, the Uppsala Longitudinal Study of Adult Men (ULSAM; n = 1009; mean age: 71 years; baseline period: 1991-1995; median follow-up: 12.6 years; end of follow-up: 2006) and the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS; n = 987; 50% women; mean age: 70 years; baseline period: 2001-2004; median follow-up: 7.9 years; end of follow-up: 2010). The PIVUS cohort was used as the discovery cohort. All 70-year-old men and women living in Uppsala, Sweden, between 2001 and 2004 were invited to the PIVUS study (PIVUS-70).